Sally J. Pyle

Director -- Dr. Sally Pyle

(701) 777-3302 (Robertson/Sayre - Office 9)

BS, 1977 & MS, 1988 Iowa State University Ph.D., 1992 Duke University

Postdoctoral Fellowship, Pathology Departments, Brigham & Women's Hospital, Children's Hospital and Harvard Medical School, 1992-1994

Johnson & Johnson Toxicology Scholar Rutgers University, 1994-1997

Research Interests:Developmental Neurobiology, Neurotoxicology, Interactions of the Cytoskeleton

Representative Publications:

Jurgens, CWD, Boese, SJ, King, JD, Pyle, SJ, Porter, JE and Doze, VA. "Adrenergic receptor modulation of Hippocampal CA3 network activity," Epilepsy Res., 66:117-28, 2005.

Pyle, SJ, Roberts, KG and Reuhl, KR. "Delayed expression of the NFH subunit in differentiating P19 cells," Dev. Brain Res., 132(1):103-106, 2001.

Pyle, SJ and Reuhl, KR. Cytoskeletal Elements in Neurotoxicity. In: Comprehensive Toxicology. Vol. 11. Eds.: Sipes, I.G., McQueen, C.A., Gandolfi, A.J., Elsevier Science, Ltd., Cambridge, pp. 79-97, 1997.

Graham, DG, Amarnath, V, Valentine, WM, Pyle, SJ and Anthony, DC. Pathogenetic studies of hexane and carbon disulfide neurotoxicity. Crit. Rev. Toxicol. 25:91-112, 1995.

Pyle, SJ, Graham, DG and Anthony, DC. Dimethylhexanedione impairs the movement of neurofilament protein subunits, NFM and NFL, in the optic system. Neurotoxicology 15:279-286, 1994.

Pyle, SJ, Amarnath, V, Graham, DG and Anthony, DC. Decreased levels of the high molecular weight subunit of neurofilaments and accelerated neurofilament transport during the recovery phase of 2,5-hexanedione exposure. Cell Motil. Cytoskel. 26:133-143, 1993.

Pyle, SJ, Amarnath, V, Graham, DG and Anthony, DC. The role of pyrrole formation in the alteration of neurofilament transport induced during exposure to 2,5-hexanedione. J. Neuropathol. Exp. Neurol. 51:451-458, 1992.