a. Papers (peer-reviewed; h factor: 29)
1. Lekieffre,D., Ghribi,O., Callebert,J., Plotkine,M., & Boulu,R.G. (1992) Involvement of glutamic acid and adenosine in the consequences of forebrain ischemia in the rat. Circulation et Metabolisme du Cerveau 9, 31-46.
2. Lekieffre,D., Ghribi,O., Callebert,J., Allix,M., Plotkine,M., & Boulu,R.G. (1992) Inhibition of glutamate release in rat hippocampus by kynurenic acid does not protect CA1 cells from forebrain ischemia. Brain Research 592, 333-337.
3. Beaudeux,C., Dumortier,G., Ghribi,O., & Degrassat,K. (1993) Dispensing clozapine at the specialized hospital of Ville-Evrard: Report of seven hematological side effects. Journal de Pharmacie Clinique 12, 312-313.
4. Ghribi,O., Callebert,J., Plotkine,M., & Boulu,R.G. (1994) Competitive NMDA receptor blockers reduce striatal glutamate accumulation in ischaemia. NeuroReport 5, 1253-1255.
5. Ghribi,O., Callebert,J., Plotkine,M., & Boulu,R.G. (1994) Effect of kynurenic acid on the ischaemia-induced accumulation of glutamate in rat striatum. NeuroReport 5, 435-437.
6. Ghribi,O., Callebert,J., Plotkine,M., & Boulu,R.G. (1994) L-NAME modulates glutamate accumulation induced by K+-depolarization but not by forebrain ischaemia in the rat striatum. Neuroscience Letters 174, 34-38.
7. Ghribi,O., Callebert,J., Verrecchia,C., Plotkine,M., & Boulu,R.G. (1995) Blockers of NMDA-operated channels decrease glutamate and aspartate extracellular accumulation m striatum during forebrain ischaemia in rats. Fundamental and Clinical Pharmacology 9, 141-146.
8. Dumortier,G., Lochu,A., De Melo,P.C., Ghribi,O., Rabreau,D.R., Degrassat,K., & Desce,J.M. (1996) Elevated clozapine plasma concentrations after fluvoxamine initiation . American Journal of Psychiatry 153, 738-739.
9. Feldman,D., Ghribi,O., Ouary,J., Dumortier,G., Degrassat,K., & Leverge,R. (1998) Quality control of 7 drugs unit doses. Journal de Pharmacie Clinique 17, 268-271.
10. Krzywkowski,P., Ghribi,O., Gagne’,J., Chabot,C., Kar,S., Rochford,J., Massicotte,G., & Poirier,J. (1999) Cholinergic systems and long-term potentiation in memory-impaired apolipoprotein E-deficient mice. Neuroscience 92, 1273-1286.
11. Ghribi,O., Lapierre,L., Girard,M., Ohayon,M., Nalbantoglu,J., & Massicotte,G. (1999) Hypoxia-induced loss of synaptic transmission is exacerbated in hippocampal slices of transgenic mice expressing C-terminal fragments of Alzheimer amyloid precursor protein. Hippocampus 9, 201-205.
12. Furling,D*., Ghribi,O*., Lahsaini,A., Mirault,M.E., & Massicotte,G. (2000) Impairment of synaptic transmission by transient hypoxia in hippocampal slices: Improved recovery in glutathione peroxidase transgenic mice. Proceedings of the National Academy of Sciences of the United States of America 97, 4351-4356. * Both authors contributed equally.
13. Cyr,M., Ghribi,O., & Di Paolo,T. (2000) Regional and selective effects of oestradiol and progesterone on NMDA and AMPA receptors in the rat brain. Journal of Neuroendocrinology 12, 445-452.
14. Valastro,B., Ghribi,O., Poirier,J., Krzywkowski,P., & Massicotte,G. (2001) AMPA receptor regulation and LTP in the hippocampus of young and aged apolipoprotein E-deficient mice. Neurobiology of Aging 22, 9-15.
15. Ghribi,O., DeWitt,D.A., Forbes,M.S., Herman,M.M., & Savory,J. (2001) Co-involvement of mitochondria and endoplasmic reticulum in regulation of apoptosis: Changes in cytochrome c, Bcl-2 and Bax in the hippocampus of aluminum-treated rabbits. Brain Research 903, 66-73.
16. Ghribi,O., DeWitt,D.A., Forbes,M.S., Arad,A., Herman,M.M., & Savory,J. (2001) Cyclosporin A inhibits Al-induced cytochrome c release from mitochondria in aged rabbits. Journal of Alzheimer's Disease 3, 387-391.
17. Savory,J., Ghribi,O., Forbes,M.S., & Herman,M.M. (2001) Aluminium and neuronal cell injury: Inter-relationships between neurofilamentous arrays and apoptosis. Journal of Inorganic Biochemistry 87, 15-19.
18. Ghribi,O., Herman,M.M., Forbes,M.S., DeWitt,D.A., & Savory,J. (2001) GDNF protects against aluminum-induced apoptosis in rabbits by upregulating Bcl-2 and Bcl-X L and inhibiting mitochondrial Bax translocation. Neurobiology of Disease 8, 764-773.
19. Ghribi,O., Herman,M.M., DeWitt,D.A., Forbes,M.S., & Savory,J. (2001) A+¦(1-42) and aluminum induce stress in the endoplasmic reticulum in rabbit hippocampus, involving nuclear translocation of gadd 153 and NF-+¦B. Molecular Brain Research 96, 30-38.
20. Cyr,M., Ghribi,O., Thibault,C., Morissette,M., Landry,M., & Di Paolo,T. (2001) Ovarian steroids and selective estrogen receptor modulators activity on rat brain NMDA and AMPA receptors. Brain Research Reviews 37, 153-161.
21. Calon,F., Morissette,M., Ghribi,O., Goulet,M., Grondin,R., Blanchet,P.J., B+¬dard,P.J., & DiPaolo,T. (2002) Alteration of glutamate receptors in the striatum of dyskinetic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys following dopamine agonist treatment. Progress in Neuro-Psychopharmacology and Biological Psychiatry 26, 127-138.
22. Forbes,M.S., Ghribi,O., Herman,M.M., & Savory,J. (2002) Aluminum-induced dendritic pathology revisited: Cytochemical and electron microscopic studies of rabbit cortical pyramidal neurons. Annals of Clinical and Laboratory Science 32, 75-86.
23. Ghribi,O., Herman,M.M., & Savory,J. (2002) The endoplasmic reticulum is the main site for caspase-3 activation following aluminum-induced neurotoxicity in rabbit hippocampus. Neuroscience Letters 324, 217-221.
24. Ghribi,O., Herman,M.M., Spaulding,N.K., & Savory,J. (2002) Lithium inhibits aluminum-induced apoptosis in rabbit hippocampus, by preventing cytochrome c translocation, Bcl-2 decrease, Bax elevation and caspase-3 activation. Journal of Neurochemistry 82, 137-145.
25. Savory,J., Ghribi,O., & Herman,M.M. (2002) Is amyloid +¦-peptide neurotoxic or neuroprotective and what is its role in the binding of metal ions? Neurobiology of Aging 23, 1089-1092.
26. Ghribi,O., Herman,M.M., & Savory,J. (2003) Lithium inhibits A+¦-induced stress in endoplasmic reticulum of rabbit hippocampus but does not prevent oxidative damage and tau phosphorylation. Journal of Neuroscience Research 71, 853-862.
27. Savory,J., Herman,M.M., & Ghribi,O. (2003) Intracellular mechanisms underlying aluminum-induced apoptosis in rabbit brain. Journal of Inorganic Biochemistry 97, 151-154.
28. Ghribi,O., Herman,M.M., Pramoonjago,P., & Savory,J. (2003) MPP + Induces the Endoplasmic Reticulum Stress Response in Rabbit Brain Involving Activation of the ATF-6 and NF-KB Signaling Pathways. Journal of Neuropathology and Experimental Neurology 62, 1144-1153.
29. Ghribi,O., Prammonjago,P., Herman,M.M., Spaulding,N.K., & Savory,J. (2003) A+¦(1-42)-induced JNK and ERK activation in rabbit hippocampus is differentially regulated by lithium but is not involved in the phosphorylation of tau. Molecular Brain Research 119, 201-206.
30. Ghribi,O., Herman,M.M., Pramoonjago,P., Spaulding,N.K., & Savory,J. (2004) GDNF regulates the A+¦-induced endoplasmic reticulum stress response in rabbit hippocampus by inhibiting the activation of gadd 153 and the JNK and ERK kinases. Neurobiology of Disease 16, 417-427.
31. Griffioen,K.J.S., Ghribi,O., Fox,N., Savory,J., & DeWitt,D.A. (2004) Aluminum maltolate-induced toxicity in NT2 cells occurs through apoptosis and includes cytochrome c release. NeuroToxicology 25, 859-867.
32. Ghribi,O. (2006) The role of the endoplasmic reticulum in the accumulation of +¦-amyloid peptide in Alzheimer's disease. Current Molecular Medicine 6, 119-133.
33. DeWitt,D.A., Hurd,J.A., Fox,N., Townsend,B.E., Griffioen,K.J.S., Ghribi,O., & Savory,J. (2006) Peri-nuclear clustering of mitochondria is triggered during aluminum maltolate induced apoptosis. Journal of Alzheimer's Disease 9, 195-205.
34. Ghribi,O., Larsen,B., Schrag,M., & Herman,M.M. (2006) High cholesterol content in neurons increases BACE, +¦-amyloid, and phosphorylated tau levels in rabbit hippocampus. Experimental Neurology 200, 460-467.
35. Savory,J., Herman,M.M., & Ghribi,O. (2006) Supplementation of the diet with silicic acid to reduce body burden of aluminum: A miracle cure or useless treatment for Alzheimer's disease? Journal of Alzheimer's Disease 10, 25-27.
36. Ghribi,O., Golovko,M.Y., Larsen,B., Schrag,M., & Murphy,E.J. (2006) Deposition of iron and +¦-amyloid plaques is associated with cortical cellular damage in rabbits fed with long-term cholesterol-enriched diets. Journal of Neurochemistry 99, 438-449.
37. Savory,J., Herman,M.M., & Ghribi,O. (2006) Mechanisms of aluminum-induced neurodegeneration in animals: Implications for Alzheimer's disease. Journal of Alzheimer's Disease 10, 135-144.
38. Ghribi,O. (2006) Preservation of the blood brain barrier integrity may underlie neuroprotective effects of statins in Alzheimer's disease. Journal of Alzheimer's Disease 10, 407-408.
39. Savory,J. & Ghribi,O. (2007) Can studies of aluminum toxicity in vivo and in vitro provide relevant information on the pathogenesis and etiology of Alzheimer's disease? Journal of Alzheimer's Disease 11, 429-430.
40. Chen,X., Ghribi,O., & Geiger,J.D. (2008) Rabbits fed cholesterol-enriched diets exhibit pathological features of inclusion body myositis. American Journal of Physiology - Regulatory Integrative and Comparative Physiology 294, R829-R835.
41. Schrag,M., Sharma,S., Brown-Borg,H., & Ghribi,O. (2008) Hippocampus of Ames dwarf mice is resistant to β-amyloid-induced tau hyperphosphorylation and changes in apoptosis-regulatory protein levels. Hippocampus 18, 239-244.
42. Chen,X., Gawryluk,J.W., Wagener,J.F., Ghribi,O., & Geiger,J.D. (2008) Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease. Journal of Neuroinflammation 5. Ref ID: 43
43. Jaya Prasanthi,R.P., Schommer,E., Thomasson,S., Thompson,A., Feist,G., & Ghribi,O. (2008) Regulation of +¦-amyloid levels in the brain of cholesterol-fed rabbit, a model system for sporadic Alzheimer's disease. Mechanisms of Ageing and Development 129, 649-655.
44. Rantham Prabhakara,J.P., Feist,G., Thomasson,S., Thompson,A., Schommer,E., & Ghribi,O. (2008) Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and +¦-synuclein in human neuroblastoma SH-SY5Y cells. Journal of Neurochemistry 107, 1722-1729.
45. Ghribi,O. (2008) Potential mechanisms linking cholesterol to Alzheimer's disease-like pathology in rabbit brain, hippocampal organotypic slices, and skeletal muscle. Journal of Alzheimer's Disease 15, 673-684.
46. Sharma,S., Prasanthi,R.P., Schommer,E., Feist,G., & Ghribi,O. (2008) Hypercholesterolemia-induced A+¦ accumulation in rabbit brain is associated with alteration in IGF-1 signaling. Neurobiology of Disease 32, 426-432.
47. Prasanthi,J.R.P., Huls,A., Thomasson,S., Thompson,A., Schommer,E., & Ghribi,O. (2009) Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on +¦-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells. Molecular Neurodegeneration 4.
48. Wu,M., Audet,A., Cusic,J., Seeger,D., Cochran,R., & Ghribi,O. (2009) Broad DNA repair responses in neural injury are associated with activation of the IL-6 pathway in cholesterol-fed rabbits. Journal of Neurochemistry 111, 1011-1021.
49. Marwarha,G., Dasari,B., Prasanthi,J.R.P., Schommer,J., & Ghribi,O. (2010) Leptin reduces the accumulation of A+¦ and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices. Journal of Alzheimer's Disease 19, 1007-1019.
50. Chen,X., Ghribi,O., & Geiger,J.D. (2010) Caffeine protects against disruptions of the blood-brain barrier in animal models of Alzheimer's and Parkinson's diseases. Journal of Alzheimer's Disease 20, S127-S141.
51. Dasari,B., Prasanthi,J.R., Marwarha,G., Singh,B.B., & Ghribi,O. (2010) The oxysterol 27-hydroxycholesterol increases +¦-amyloid and oxidative stress in retinal pigment epithelial cells. BMC Ophthalmology 10.
52. Marwarha,G., Dasari,B., Prabhakara,J.P.R., Schommer,J., & Ghribi,O. (2010) +¦-Amyloid regulates leptin expression and tau phosphorylation through the mTORC1 signaling pathway. Journal of Neurochemistry 115, 373-384.
53. Prasanthi,J.R.P., Dasari,B., Marwarha,G., Larson,T., Chen,X., Geiger,J.D., & Ghribi,O. (2010) Caffeine protects against oxidative stress and Alzheimer's disease-like pathology in rabbit hippocampus induced by cholesterol-enriched diet. Free Radical Biology and Medicine 49, 1212-1220.
54. Chen,X., Wagener,J.F., Morgan,D.H., Hui,L., Ghribi,O., & Geiger,J.D. (2010) Endolysosome mechanisms associated with Alzheimer's disease-like pathology in rabbits ingesting cholesterol-enriched diet. Journal of Alzheimer's Disease 22, 1289-1303.
55. Marwarha,G., Prasanthi,J.R., Schommer,J., Dasari,B., & Ghribi,O. (2011) Molecular interplay between leptin, insulin-like growth factor-1, and +¦-amyloid in organotypic slices from rabbit hippocampus. Molecular Neurodegeneration 6.
56. Dasari,B., Prasanthi,J.R., Marwarha,G., Singh,B.B., & Ghribi,O. (2011) Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina. BMC Ophthalmology 11.
57. Prasanthi,J.R.P., Larson,T., Schommer,J., & Ghribi,O. (2011) Silencing gadd153/chop gene expression protects against alzheimer's disease-like pathology induced by 27-hydroxycholesterol in rabbit hippocampus. PLoS ONE 6.
58. Prasanthi, R. P. J., Marwarha, G., and Ghribi, O. The cholesterol-fed rabbit as a model system for cholesterol-Alzheimer's disease studies. 1, 163-178. 2011.
59. Marwarha,G., Rhen,T., Schommer,T., & Ghribi,O. (2011) The oxysterol 27-hydroxycholesterol regulates +¦-synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen receptors-relevance to Parkinson's disease. Journal of Neurochemistry 119, 1119-1136.
60. Marwarha,G. & Ghribi,O. (2012) Cellular model of Alzheimer's disease - Relevance to therapeutic testing. Experimental Neurology 233, 733-739.
61. Marwarha,G., Dasari,B., & Ghribi,O. (2012) Endoplasmic reticulum stress-induced CHOP activation mediates the down-regulation of leptin in human neuroblastoma SH-SY5Y cells treated with the oxysterol 27-hydroxycholesterol. Cellular Signalling 24, 484-492.
62. Liu,R., Lei,J.X., Luo,C., Lan,X., Chi,L., Deng,P., Lei,S., Ghribi,O., & Liu,Q.Y. (2012) Increased EID1 nuclear translocation impairs synaptic plasticity and memory function associated with pathogenesis of Alzheimer's disease. Neurobiology of Disease 45, 902-912.
63. Prasanthi,J.R.P., Schrag,M., Dasari,B., Marwarha,G., Dickson,A., Kirsch,W.M., & Ghribi,O. (2012) Deferiprone reduces amyloid-+¦ and tau phosphorylation levels but not reactive oxygen species generation in hippocampus of rabbits fed a cholesterol-enriched diet. Journal of Alzheimer's Disease 30, 167-182.
64. Zhang,H., Wang,Z., Stupak,J., Ghribi,O., Geiger,J.D., Liu,Q.Y., & Li,J. (2012) Targeted glycomics by selected reaction monitoring for highly sensitive glycan compositional analysis. Proteomics 12, 2510-2522.
- Mital Y. Patel, Hirenkumar V. Panchal, Othman Ghribi, and Kenza E. Benzeroual. (2012) The neuroprotective effect of fisetin in the MPTP model of Parkinson’s disease. Journal of Parkinson’s Disease 2: 287-302
66 Gurdeep Marwarha, Othman Ghribi (2012) Leptin signaling and Alzheimer’s disease. Am J Neurodegener Dis 1:245-265
67 Bhanu Dasari, Jaya RP Prasanthi, Craig Meiers, Brij B Singh, Othman Ghribi. (2013) Differential effects of the estrogen receptor agonist estradiol on toxicity induced by enzymatically-derived or autoxidation-derived oxysterols in human ARPE-19 cells. Current Eye Research 2013.
68 Gurdeep Marwarha, Shaneabbas Raza, Jaya R.P Prasanthi, and Othman Ghribi. (2013)Gadd153 and NF-κB crosstalk regulates 27-hydroxycholesterol-induced increase in BACE1 and β-amyloid production in human neuroblastoma SH-SY5Y cells. PLoS ONE 2013 Aug 9;8(8):e70773. doi: 10.1371/journal.pone.0070773.
69 Schrag M, Mueller C, Zabel M, Crofton A, Kirsch WM, Ghribi O, Squitti R, Perry G. Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: A meta-analysis. Neurobiol Dis. 2013 Jul 15. pii: S0969-9961(13)00199-X. doi: 10.1016/j.nbd.2013.07.005
70 Qing Yan Liu, Marilyn N. Vera Chang, Joy X Lei, Roger Koukiekolo, Brandon Smith, Dongling Zhang and Othman Ghribi (2014) Identification of microRNAs involved in Alzheimer’s progression using a rabbit model of the disease. Am J Neurodegener Dis. 2014 Mar 28;3(1):33-44.
71 Marwarha G, Raza S, Meiers C, Ghribi O. Leptin attenuates BACE1 expression and amyloid-β genesis via the activation of SIRT1 signaling pathway. Biochim Biophys Acta. 2014;1842(9):1587-95
72 Danielle Morgan, Othman Ghribi, Liang Hui, Jonathan D. Geiger, and Xuesong Chen. Cholesterol-enriched diet disrupts the blood-testis barrier in rabbits. American Journal of Physiology - Endocrinology and Metabolism 2014;307(12):E1125-30
73 Kate J. Claycombe, Catherine Brissette, and Othman Ghribi. Epigenetics of inflammation, maternal infection, and nutrition. J Nutr. 2015 May;145(5):1109S-15S
74 Kate J. Claycombe, Emilie E. Vomhof-DeKrey, James N. Roemmich, Amy Bundy, Turk Rhen, and Othman Ghribi. Maternal low protein diet causes body weight loss in male, neonate Sprague-1 Dawley rats involving UCP-1 mediated thermogenesis. J Nutr Biochem. 2015 Jul;26 (7):729-35.
75 Marwarha G, Ghribi O. Does the oxysterol 27-hydroxycholesterol underlie Alzheimer's disease-Parkinson's disease overlap? Exp Gerontol. 2015 Aug; 68:13-8.
76 Shaneabbas Raza, Joyce E Ohm, Archana Dhasarathy, Jared Schommer, Conor Roche, Kimberly DP Hammer, and Othman Ghribi.. The cholesterol metabolite 27-hydroxycholesterol regulates p53 activity and increases cell proliferation via MDM2 in breast cancer cells. Molecular and Cellular Biochemistry 2015 Dec;410(1-2):187-95
77 Gurdeep Marwarha and Othman Ghribi. NF-κB – a friend, a foe, or a bystander - in the neurodegenerative cascade and pathogenesis of Alzheimer’s disease. Invited Review; in revision, CNS & Neurological Disorders - Drug Targets
78 Shaneabbas Raza, Megan Meyer, Jared Schommer, Kimberly DP Hammer, Bin Guo and Othman Ghribi. 27-hydroxycholesterol stimulates cell proliferation and resistance to docetaxel-induced apoptosis in prostate epithelial cells. Medical Oncology, 2016 Feb;33(2):12. doi: 10.1007/s12032-015-0725-5
79 Qing Yan Liu, Roger Koukiekolo, Dongling Zhang, Brandon Smith, Dao Ly, Joy X Lei, and Othman Ghribi. Molecular events linking cholesterol to Alzheimer’s disease and inclusion body myositis in a rabbit model. Am J Neurodegener Dis 2016;5(1):74-84
80 Shaneabbas Raza, Megan Meyer, Casey Goodyear, Kimberly DP Hammer, Bin Guo and Othman Ghribi. The cholesterol metabolite, 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells. (In revision)
81 Shaneabbas Raza and Othman Ghribi. 27-hydroxycholesterol: A new player in hormonal cancers. The Journal of Steroid Biochemistry and Molecular Biology (in revision)
82 Emilie Vomhof-DeKrey Diane Darland, Othman Ghribi, Amy Bundy, James Roemmich, Kate Claycombe. Maternal low protein diet leads to placental angiogenic compensation via dysregulated M1/M2 macrophages and TNFα expression in Sprague-Dawley rats. Journal of Reproductive Immunology (in press)
83 Chen X, Wagener JF, Ghribi O, Geiger JD. Role of Endolysosomes in Skeletal Muscle Pathology Observed in a Cholesterol-Fed Rabbit Model of Alzheimer's Disease. Front Aging Neurosci. 2016 Jun 8;8:129. doi: 10.3389/fnagi.2016.00129.
84 Gurdeep Marwarha, Kate Claycomb, Jared Schommer, David Collins, and Othman Ghribi. Palmitate-induced Endoplasmic Reticulum stress and subsequent C/EBPα Homologous Protein activation attenuates leptin and Insulin-like Growth Factor 1 expression in the brain. Cell Signal. 2016 Aug 20;28 (11):1789-1805.
- Invited oral presentations
- Palmitate-induced ER Stress and Subsequent CHOP Activation Attenuates Leptin and IGF1 Expression – Implications for Alzheimer’s Disease, 2nd Neurological Disorders Summit. September 07-09, 2016 DoubleTree By Hilton, Baltimore, MD, USA
- Regulation of α-synuclein levels by 27-hydroxycholesterol-Relevance to Synucleinopathies. Current Trends in Oxysterols and related sterols: Biological and Medical aspects, The European Network for Oxysterol Research. September 29-30, Paris Descartes.
- The cholesterol oxidation products may underlie α-synuclein accumulation in Alzheimer’s disease and Parkinson’s disease. Controversy in Neurology, Lisbon, Portugal March 17-22, 2016
- The Multi-Faceted Actions of the Cholesterol Oxidation Products in Health and Disease. 103rd Indian Science Congress, Mysore University, India January 2016.
- Oxysterols and Neurodegenerative diseases. International Conference on Neurology and Epidemiology, 5th Scientific meeting, Gold Coast, Australia, November 2015
- Oxysterols-Multifaceted players in neurodegenerative disease. Neurological Disorders Summit; San Francisco, July 06-08, 2015
- Oxysterols in Alzheimer’s disease. Abbott/Abbvie laboratories, Chicago, IL. October 29th, 2014
- Does the oxysterol 27-hgydroxycholesterol underlie Alzheimer’s disease/Parkinson’s disease overlap? The 12th International symposium on neurobiology and neuroendocrinology of aging, Bregenz, Austria, July 2014.
- The role of the oxysterol 27-hydroxycholesterol in Alzheimer’s disease-like pathology. Loma Linda University, January 30th, 2014 (Host: Dr. Soriano).
- The multifaceted roles of the oxysterol 27-hydroxycholesterol. West Virginia University at Morgantown, December 3, 2013 (Host: Dr. Schreurs).
- Saturated free fatty acid consumption may increase the risk for Alzheimer’s disease. Nanosymposium on Alzheimer’s disease and inflammation, Neuroscience meeting, October 2012, New Orleans.
- Alzheimer’s disease and Parkinson’s disease overlap-A role for Oxysterols? International Conference and Exhibition on Neurology & Therapeutics-Novel Therapies in Neurosciences, May 14, 2012. Las Vegas, NV.
- Cholesterol and Age-Related Macular Degeneration. Loma Linda School of Medicine, June 2, 2011 (Host Dr. Kirsch).
- Regulation of Tyrosine hydroxylase and α-synuclein levels by LXR and estrogen receptors-relevance to Parkinson’s disease. The 10th Annual International Conference AD/PD, Barcelona, Spain, March 9-13, 2011.
- Cholesterol and Alzheimer’s disease-Is there a connection? The Alzheimer's Association Minnesota-North Dakota Chapter. Minneapolis, March 19, 2011.
- Cholesterol and Alzheimer’s disease. Annual conference sponsored by St. Alexius, the ND Hospice Organization, and the Alzheimer's Association Minnesota-North Dakota. Bismarck, ND October 16, 2009.
- Common pathological hallmarks for Alzheimer’s disease and age-related macular degeneration in the cholesterol-fed rabbit model. Department of Anatomy, University of North Dakota School of Medicine. November 2, 2009
- Oxysterols alter expression levels of tyrosine hydroxylase, alpha-synuclein, and beta-amyloid: relevance to Parkinson’s and Alzheimers’s diseases. The 9th Annual International Conference AD/PD, Prague, Czech Republic, March 11-15, 2009.
- Cholesterol-Induced Alzheimer’s Disease-like pathology in rabbit brain. Loma Linda University, School of Medicine, January 4th 2008.
- Alzheimer’s disease: social impact and care givers role. Department of Sociology, University of North Dakota, February 7th 2008.
- Nutrition and neurodegenerative disorders. University Senghor, Alexandria, Egypt, February 2008.
- Alzheimer Disease: a cause of pathological aging. Department of Sociology, University of North Dakota, February 9, 2006
- Cholesterol-Induced Oxidative Stress & the Pathogenesis of Alzheimer’s Disease. Department of Anatomy, University of North Dakota School of Medicine. November 21st, 2005.
- Neurotoxic Injury: Regulation by Mitochondrial-Endoplasmic Reticulum Cross-talk. University of Quebec at Trois-Rivieres, March 2004.
- Ab(1-42)-induced phosphorylation of tau and apoptosis in an in vivo model: mechanisms and pathways. St Elizabeth Medical Center, Boston, MA, January 7, 2004.
- Mechanisms of Neuronal Death in Experimental Degeneration, DRDC Suffield, Alberta, Canada, June 2003.
- Lithium inhibits Aß-induced caspase-3 activation, GSK-3 AND JNK phosphorylation, but not oxidative stress, in rabbit brain hippocampus. The 8th international conference on Alzheimer’s disease and related disorders. Stockholm, Sweden, July 20-25, 2002. Neurobiology of aging 23 (1): 510 Suppl. 1 JUL-AUG 2002
- Mitochondrial injury and apoptosis in Aluminum-induced neurotoxicity. Robert O. Lawson Chair in Neural Repair and Regeneration, Head Spinal Program, Toronto Western Hospital, University Health Network, January 8, 2001.
- Changes in protein-regulating apoptosis in an experimental model of neurodegeneration: Institute of Biological Sciences, NRC, Ottawa, Canada, February 2, 2001
- Local NMDA receptor blockade decreases extracellular glutamate and aspartate levels during forebrain ischaemia in rat striatum. 50th meeting of l'Association Française des Pharmacologistes. Lille, October 6-9, 1993. Fund. Clin. Pharmacol, 7:360, 1993.
- Les antagonistes des récepteurs NMDA réduisent l'accumulation des acides aminés excitateurs induite par une ischémie cérébrale chez le rat. Circulation et Métabolisme du Cerveau, 10:168-176 1993.
- Kynurenic acid but not MK-801 reduces the extracellular amino acid accumulation in rat striatum and hippocampus during cerebral ischaemia. 48th Meeting of l'Association Française des Pharmacologistes. Montpelier, October 1-2, 1992. Fund. Clin. Pharmacol. 6:393, 1992.