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  • Bo Liang
Portrait of Bo Liang

Bo Liang

  • Asst Prof Biomedcl Engineering, SEECS

Contact Info

  • Email: bo.liang@UND.edu
  • Office: 701.777.5449
  • Dept: 701.777.5790

Office Address

Upson II Room 366L
243 Centennial Drive Stop 7165
Grand Forks ND 58202-7165

Biography

Bo Liang is an assistant professor of Biomedical Engineering at the School of Electrical Engineering and Computer Science, University of North Dakota. His research interests include optical imaging and instrumentation, neurophotonics, and neural data processing. Prior to joining UND, he conducted his postdoctoral research at the National Institute on Drug Abuse Intramural Research Program, NIH. He earned a bachelor’s degree in Biomedical Engineering from Huazhong University of Science and Technology in 2008 and his Ph.D. in Optical Engineering from the University of Chinese Academy of Sciences in 2013.

BME432/690 Fundamentals of Biomedical Optics (2022 Spring)

EECS590 Computational imaging (2021 Fall)

BME690 Fundamentals of Biomedical Optics (2021 Spring)

  • Optical imaging and instrumentation
  • Neurophotonics
  • Neural data processing

2022

  • Barbera, G., Jun, R., Zhang, Y., Liang, B., Li, Y., & Lin, D. T. (2022). A miniature fluorescence microscope for multi-plane imaging. Scientific reports, 12(1), 1-8.
  • Liang, B., Thapa, R., Zhang, G., Moffitt, C., Zhang, Y., Zhang, L., ... & Li, Y. (2022). Aberrant Neural Activity in Prefrontal Pyramidal Neurons Lacking TDP-43 Precedes Neuron loss. Progress in Neurobiology, 102297.
  • Liang, B., Zhang, L., Zhang, Y., Werner, C.T., Beacher, N.J., Denman, A.J., Li, Y., Chen, R., Gerfen, C.R., Barbera, G. and Lin, D.T., 2022. Striatal direct pathway neurons play leading roles in accelerating rotarod motor skill learning. iScience, p.104245.
  • Zhang, Y., Denman, A.J., Liang, B., Werner, C.T., Beacher, N.J., Chen, R., Li, Y., Shaham, Y., Barbera, G. and Lin, D.T., 2022. Detailed mapping of behavior reveals the formation of prelimbic neural ensembles across operant learning. Neuron, 110(4), pp.674-685.

2021

  • Thapa R, Liang B, Liu R, Li Y. Stereotaxic Viral Injection and Gradient-Index Lens Implantation for Deep Brain In Vivo Calcium Imaging. J Vis Exp. 2021 Oct 8;(176). doi: 10.3791/63049. PMID: 34694282.

2020

  • Barbera G., Zhang Y., Werner C., Liang B., Li Y., Lin D-T (2020). An open source motorized swivel for in vivo neural and behavioral recordings. MethodsX, 7, 101167. 
  • Barbera G., Liang B., Zhang Y., Moffitt C., Li Y., Lin D-T (2020). An open-source capacitive touch sensing device for three chamber social behavior test. MethodsX, 7, 101024. 

2019

  • Wu J., Kung J., Dong J., Chang L., Xie C., Habib A., Hawes S., Yang N., Chen V., Liu Z., Evans R., Liang B., Sun L., Ding J., Yu J., Saez-Atienzar S., Tang B., Khaliq Z., Lin D-T., Le W., Cai H (2019). Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning. Cell Reports 28(5): 1167-1181.e7.
  • Barbera G., Liang B., Zhang L., Li Y., Lin D.T. (2019). A wireless miniScope for deep brain imaging in freely moving mice. J Neurosci Methods 323, 56-60.
  • Liang, B. *, Zhang, L. *, Moffitt, C., Li, Y., and Lin, D.T. (2019). An Open-source Automated Surgical Instrument for Microendoscope Implantation. J Neurosci Methods 311, 83-88. (*Corresponding authors)
  • Yang, Y., Zhang, L., Wang, Z., Liang, B., Barbera, G., Moffitt, C., Li, Y., and Lin, D.T (2019). A Two-Step GRIN Lens Coating for in vivo Brain Imaging. Neuroscience Bulletin 1-6.

2018

  • Liang, B.*, Zhang, L.*, Barbera, G., Fang, W., Zhang, J., Chen, X., Chen, R., Li, Y., and Lin, D.T. (2018). Distinct and Dynamic ON and OFF Neural Ensembles in the Prefrontal Cortex Code Social Exploration. Neuron 100, 700-714.e9. (*Co-first authors) [ Neuron preview; NIDA news]
  • Zhang, L. *, Liang, B. *, Barbera, G. *, Hawes, S., Zhang, Y., Stump, K., Baum, I., Yang, Y., Li, Y., and Lin, D.T. (2018). Miniscope GRIN Lens System for Calcium Imaging of Neuronal Activity from Deep Brain Structures in Behaving Animals. Curr Protoc Neurosci, e56. (*Co-first authors)

2017

  • Zhang W, Daly KM, Liang B, Zhang LF, Li, X, Li Y, Lin DT. (2017). BDNF Rescues Prefrontal Dysfunction Elicited by Pyramidal Neuron Specific DTNBP1 Deletion In Vivo. J Mol Cell Biol 9(2):117-131.
  • Zhang, L., Liang, B., Li, Y. and Lin, D. (2017). Thinned-skull Cranial Window Preparation (Mice). Bio-protocol7(5): e2158.

2016

  • Barbera G*, Liang B*, Zhang LF*, Gerfen CR, Culurciello E, Chen R, Li Y, Lin DT (2016). Spatially Compact Neural Clusters in the Dorsal Striatum Encode Locomotion Relevant Information. Neuron 92(1):202-213 (*Co-first authors) [NIDA news; Neuron Video Abstract Featured]
  • Zhang W*, Zhang LF*, Liang B, Schroeder D, Zhang ZW, Cox GA, Li Y, Lin DT (2016). Hyperactive Somatostatin Interneurons Contribute to Excitotoxicity in Neurodegenerative Disorders. Nature Neuroscience 19, 557–559. [News highlights]

Before 2014

  • Liang B, Dai Y, Zhao HX, Zhang YD (2013). Effect of Ocular Aberrations on Binocular Summation in Different Light Levels. Opto-Electronic Engineering 40(7): 1-8.
  • Yang, B, Liang, B, Liu, L, Liao, M, Li, Q, Dai, Y, Zhao, HX, Zhang, Y., & Zhou, Y. (2013). Contrast Sensitivity Function after Correcting Residual Wavefront Aberrations during RGP Lens Wear. Optometry & Vision Science 91(10):1271-7.
  • Liang, B, Liu, R, Dai, Y, Zhou, JW, Zhou, YF, & Zhang, YD (2012). Effects of Ocular Aberrations on Contrast Detection in Noise. Journal of Vision, 12(8):3, 1–15.
  • Zhou, JW, Zhang, YD, Dai, Y, Zhao, HX, Liu, R, Hou, F., Liang, B, Hess, RF & Zhou, YF (2012). The Eye Limits the Brain’s Learning Potential. Scientific Reports 2, 364. 
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