Clinical and Translational Science Ph.D.

BIMD 516. Responsible Conduct of Research. 2 Credits.

A series of lectures and discussion sessions covering topics related to responsible conduct in research. Students will examine a variety of issues including introduction to ethical decision making, the experience of conflict, laboratory practices, data management, reporting of research, conflict of interest, and compliance. Examples and case studies will be drawn primarily from the biomedical sciences. F.

PATH 500. Biochemistry and Cell Biology. 6 Credits.

Knowledge in biochemistry and cell biology form the core concepts that underlay all study and research endeavors in the clinical sciences. Since the basics in these two disciplines are paramount to a successful graduate studies program, the course is designed to emphasize proficiency in basic concepts. The course is highly didactic and makes no assumptions of previous educational experiences of the incoming graduate student. This is deemed essential for a course that forms the stem in a multi-disciplinary graduate program. Thus the course is focused on basic textbook-based foundational knowledge and problem solving skills. The course begins by relating basic general and organic chemistry to biochemical systems, followed by addressing actual biochemical, synthetic and degradation reactions, and expanding this to the macromolecular and cell biological components of the process. Thus the study is first presented with the biochemical and molecular aspects of cellular processes and then uses this to build a more comprehensive picture of how molecular structures come together to forms structures visible by various forms of microscopy. F.

PATH 575. Molecular and Pathological Basis of Human Disease. 4 Credits.

Pathogenesis of Human Disease is an advanced graduate course that is based on lectures and discussions with a strong element of self-study through the use of extensive reading materials as well as lecture videos. This course is intended to cover aspects of the fundamental molecular, cellular and pathological mechanisms underlying various human diseases while the courses offered in the various CTS 590 special topics course will focus on diseases of specific organ systems. By the end of this course the student will have demonstrated a significant knowledge base of the molecular and pathological basis of human disease that is applicable to clinical and translational research. The student will also have sufficient knowledge of pathology to be capable of teaching this material to medical, professional, and graduate students. This course is open to all graduate students in the School of Medicine and Health Sciences as well as graduate students in biological sciences enrolled at the University of North Dakota who meet the prerequisites. Prerequisite: MBIO 509, PATH 500, and ANAT 517. F.

BIMD 510. Basic Biomedical Statistics. 2 Credits.

A series of lectures, demonstrations and exercises to provide students with the basic rationales for the use of statistics in the assessment of biomedical data and a selected set of the most common and useful statistical tests. Prerequisite: BIMD 500 or permission of course director. S.