Clinical and Translational Science

BIMD 516. Responsible Conduct of Research. 2 Credits.

A series of lectures and discussion sessions covering topics related to responsible conduct in research. Students will examine a variety of issues including introduction to ethical decision making, the experience of conflict, laboratory practices, data management, reporting of research, conflict of interest, and compliance. Examples and case studies will be drawn primarily from the biomedical sciences. F.

PATH 500. Biochemistry and Cell Biology. 6 Credits.

Knowledge in biochemistry and cell biology form the core concepts that underlay all study and research endeavors in the clinical sciences. Since the basics in these two disciplines are paramount to a successful graduate studies program, the course is designed to emphasize proficiency in basic concepts. The course is highly didactic and makes no assumptions of previous educational experiences of the incoming graduate student. This is deemed essential for a course that forms the stem in a multi-disciplinary graduate program. Thus the course is focused on basic textbook-based foundational knowledge and problem solving skills. The course begins by relating basic general and organic chemistry to biochemical systems, followed by addressing actual biochemical, synthetic and degradation reactions, and expanding this to the macromolecular and cell biological components of the process. Thus the study is first presented with the biochemical and molecular aspects of cellular processes and then uses this to build a more comprehensive picture of how molecular structures come together to forms structures visible by various forms of microscopy. F.

PATH 505. Seminar in Clinical and Translational Science. 1 Credit.

All students and faculty within the program will participate in longitudinal seminars discussing their research area and interrelationships with complimentary disciplines. This may be in form of discussions, "chalk talks" of current efforts, literature or topic review. This will give students and faculty interdisciplinary and collaborative exposure to broad areas of inquiry and foster creativity and collaboration. This course will be taken annually by all students in the CTS program. Repeatable to 11.00 credits. S/U grading. F,S.

BIMD 510. Basic Biomedical Statistics. 2 Credits.

A series of lectures, demonstrations and exercises to provide students with the basic rationales for the use of statistics in the assessment of biomedical data and a selected set of the most common and useful statistical tests. Prerequisite: BIMD 500 or permission of course director. S.

PATH 590. Readings. 1-3 Credits.

The primary goal of this course is for students to learn critical thinking and data analysis of the literature in their field of research study. Course sections will range from general training to journal clubs with an advanced topic focus. 1-3 credits There are two modes of this course 1)CTS 590 Readings: Scientific Reading This course is designed to promote critical reading of the literature. The primary goal is to teach students the process by which scientists identify problems, formulate testable hypotheses, collect data through experiments, and eventually establish new models describing biological processes. 1 credit 2)CTS 590 Readings: Journal Club The goal of the journal club is to familiarize students with the most up-to-date scientific literature and to develop the tools necessary to be a life-long learner. Students led by a faculty facilitator will discuss experimental methods and observations and this will provide graduate students the opportunity to develop oral skills. The course will also facilitate scientific communication between various clinical disciplines. The prerequisite for this course is CTS590 Readings: Scientific Reading; or equivalent with permission from course director. Repeatable to 3.00 credits. S/U grading. F,S.

PATH 593. Research. 1-6 Credits.

Research experience is offered in the specialty fields of the faculty within the Clinical and Translational Science Program and involves an intensive research experience on a variety of unique research problems utilizing modern methods and tools. Credits arranged (generally 1-6 credits per semester). Repeatable. F,S,SS.